Levitra is a prescription medicine whose active ingredient is vardenafil. It belongs to a class of drugs known as phosphodiesterase type 5 inhibitors (PDE5 inhibitors). Levitra facilitates erection by enhancing the natural relaxant effects of nitric oxide in the penile tissue, which increases blood flow to the corpus cavernosum when sexual stimulation occurs.
Unlike vasodilators that act systemically, vardenafil selectively targets PDE5 in the smooth muscle cells lining the blood vessels of the penis. By inhibiting PDE5, the enzyme that breaks down cyclic guanosine monophosphate (cGMP), vardenafil prolongs the cGMP-mediated vasodilation needed for a firm, lasting erection.
Levitra is effective only in the presence of sexual arousal. It does not increase sexual desire or treat hormonal causes of impotence. The onset of action is typically within 25–60 minutes of oral administration, with an effective window that can extend up to 5 hours, depending on individual metabolism, dose and comorbid factors.
A generic Levitra preparation contains the same active molecule, vardenafil, at the same dosage strength as the branded product. The generic must demonstrate bioequivalence to the reference drug, ensuring the same pharmacokinetic and pharmacodynamic profile. Inactive ingredients, tablet color, shape and packaging may vary between manufacturers.
Individual patient perception can differ due to excipient variations, taste, coating or tablet dissolution. If switching from branded to generic, patients should monitor response and report any unexpected changes in efficacy or tolerability.
In the UK, vardenafil is classified as a Prescription Only Medicine (POM). However, through private online pharmacies and doctor-led assessment services, qualified clinicians can provide remote patient assessments and legal prescriptions as part of the purchase process.
Markeaton Pharmacy partners with registered prescribers to offer fast delivery of vardenafil after an online consultation. This approach ensures that contraindications and interactions are screened, and patients receive personalised advice on safe use.
Ordering without a valid prescription from an MHRA-licensed prescriber remains illegal and insecure. Patients should avoid unverified websites offering unlicensed products, as these may contain incorrect strengths, contaminants or counterfeits.
Vardenafil is available in the UK in 5 mg, 10 mg and 20 mg tablet strengths. The starting dose for most patients is 10 mg, taken approximately one hour before sexual activity. Depending on efficacy and tolerability, the dose may be increased to 20 mg or decreased to 5 mg.
Levitra tablets are coated film tablets designed for oral administration. Generic versions may use alternative coatings or shapes. All formulations should be taken whole with water, and tablets should not be chewed, split or crushed.
Do not take more than one dose of vardenafil in 24 hours. Food, especially high-fat meals, may delay absorption and onset of action. Alcohol should be consumed in moderation as it can impair erection and increase side effects.
Prices vary according to pack size, dosage strength, manufacturer and pharmacy retailer. Below is an illustrative example for guidance. Actual prices and availability should be checked with Markeaton Pharmacy.
| Product | Strength | Pack size | Price (GBP) | Status | Note |
|---|---|---|---|---|---|
| Generic Vardenafil A | 10 mg | 4 tablets | £19.99 | In stock | Fast UK delivery |
| Generic Vardenafil B | 10 mg | 8 tablets | £34.99 | In stock | Discount pack option |
| Generic Vardenafil C | 20 mg | 4 tablets | £29.99 | Pre-order | Subject to clinic review |
Pack size and strength determine the total amount of active drug. Bulk packs typically offer a lower per-tablet price. Manufacturer discounts, pharmacy promotions and membership schemes can further reduce cost. Markeaton Pharmacy offers price-match on genuine UK-sourced generics.
To secure the best price on generic vardenafil:
Ensure any discount does not compromise safety: only purchase from MHRA-registered online pharmacies like Markeaton Pharmacy.
Vardenafil is generally well tolerated. The most frequently reported adverse events are dose-related and mild or moderate in intensity.
| System | Common effects |
| Nervous system | Headache, dizziness |
| Gastrointestinal | Indigestion, nausea |
| Musculoskeletal | Back pain |
| Vision | Flushing, nasal congestion |
| Cardiovascular | Palpitations (rare) |
Side effects often diminish as the body adjusts. If persistent or severe, consult a healthcare professional. Seek immediate help if priapism (erection lasting >4 hours) or sudden vision/hearing loss occurs.
Vardenafil is metabolised by CYP3A4. Potent inhibitors (e.g., ketoconazole, ritonavir) increase exposure and may require dose reduction. CYP3A4 inducers (e.g., rifampicin) can reduce efficacy.
Excessive alcohol can impair erection and increase dizziness. Smoking may worsen vascular health and ED over time.
High-fat meals delay absorption; take on an empty stomach or after a light snack for faster onset.
ED often has psychological components. Counseling, stress management, exercise and sleep hygiene can enhance overall sexual health alongside medication.
| Feature | Vardenafil (Levitra) | Sildenafil (Viagra) | Tadalafil (Cialis) |
| Onset | 25–60 min | 30–60 min | 30 min |
| Duration | Up to 5 h | 4–5 h | Up to 36 h |
| Food effect | Delayed by high-fat | Delayed by high-fat | Minimal |
| Daily dosing | No | No | Available |
Choice depends on desired duration, meal habits and individual response. Tadalafil’s longer window may suit frequent activity, while vardenafil’s potency can be preferred by others.
Older patients (>65 years) may require lower starting doses due to decreased metabolism. In mild-to-moderate renal impairment no adjustment is necessary, but severe cases warrant caution. In hepatic impairment, start at the lowest dose and extend dosing interval if needed.
Consult a clinician before vardenafil if you have a history of stroke, myocardial infarction, unstable angina or severe hypotension.
There is no evidence of tachyphylaxis with vardenafil. Regular users can continue therapy as needed. However, persistent ED may indicate underlying pathology such as cardiovascular disease or diabetes and should prompt further evaluation.
Periodic review ensures that dosing remains optimal, side effects are monitored and any new contraindications or drug interactions are identified.
Each approach has unique benefits and risks. Specialist referral may be appropriate for complex or refractory cases.
Keep in original packaging at room temperature (20–25 °C). Protect from moisture and light. Keep out of reach of children. Do not store in the bathroom or car. Discard unused tablets after the expiry date printed on the pack.
For detailed product information, consult the Summary of Product Characteristics and patient information leaflet supplied with the medicine. Reliable online sources include the MHRA and the electronic Medicines Compendium (eMC).
This information is intended as a guide from Markeaton Pharmacy, 126 Kedleston Road, Derby, DE22 1FX. It does not replace professional medical advice. For personal recommendations or concerns, speak to our pharmacy team or your healthcare provider.